DUBAI, United Arab Emirates (AP) — Israel appeared to be expanding its air campaign on Tehran five days after its surprise attack on Iran's military and nuclear program, as U.S. President Donald Trump posted an ominous message warning residents of the city to evacuate.

IRAN CAN NOT HAVE A NUCLEAR WEAPON, Trump wrote Monday night before returning to Washington early from a Group of Seven summit in Canada. Everyone should immediately evacuate Tehran! he added.

Trump later denied reports that he had rushed back to Washington to work on a ceasefire, saying his early departure has nothing to do with a Cease Fire. Much bigger than that, without elaborating.

Earlier, the Israeli military had called for some 330,000 residents of a neighborhood in the city center to evacuate. Tehran is one of the largest cities in the Middle East, with around 9.5 million people.

Israel says its sweeping assault on Iran's top military leaders, nuclear scientiests, uranium enrichment sites and ballistic missile program is necessary to prevent its longtime adversary from getting any closer to building an atomic weapon. The strikes have killed at least 224 people since Friday.

Iran has retaliated by launching more than 370 missiles and hundreds of drones at Israel. So far, 24 people have been killed in Israel and more than 500 wounded.

The back-and-forth has raised concerns about all-out war between the countries and propelled the region, already on edge, into even greater upheaval.

Before leaving the summit in Canada, Trump joined the other leaders in a joint statement saying Iran can never have a nuclear weapon and calling for a de-escalation of hostilities in the Middle East, including a ceasefire in Gaza.

Meanwhile, U.S. Defense Secretary Pete Hegseth headed to the White House Situation Room to meet with the president and his national security team.

Hegseth didn't provide details on what prompted the meeting but said on Fox News late Monday that the movements were to ensure that our people are safe.

Israeli military spokesperson Brig. Gen. Effie Defrin said Monday that his country's forces had achieved full aerial superiority over Tehran's skies.

The military said it destroyed more than 120 surface-to-surface missile launchers in central Iran, a third of Iran's total, including multiple launchers just before they launched ballistic missiles towards Israel. It also destroyed two F-14 fighter planes that Iran used to target Israeli aircraft, the military said.

Israeli military officials also said fighter jets had struck 10 command centers in Tehran belonging to Iran's Quds Force, an elite arm of its paramilitary Revolutionary Guard that conducts military and intelligence operations outside Iran.

Israel's military issued an evacuation warning to 330,000 people in a part of central Tehran that houses the country's state TV and police headquarters, as well as three large hospitals, including one owned by the Guard.

Israel's military has issued similar evacuation warnings for parts of the Gaza Strip and Lebanon ahead of strikes. Health authorities reported that 1,277 people were wounded in Iran. Iranians also reported fuel rationing.

Rights groups such as the Washington-based Iranian advocacy group Human Rights Activists have suggested that the Iranian government's death toll is a significant undercount. The group says it has documented more than 400 people killed, among them 197 civilians.

Prime Minister Benjamin Netanyahu said the Israeli strikes have set Iran's nuclear program back a very, very long time, and told reporters he is in daily touch with Trump.

Iran maintains that its nuclear program is peaceful, and the U.S. and others have assessed that Tehran has not had an organized effort to pursue a nuclear weapon since 2003. The head of the International Atomic Energy Agency has repeatedly warned that the country has enough enriched uranium to make several nuclear bombs should it choose to do so.

So far, Israel has targeted multiple Iranian nuclear program sites but has not been able to destroy Iran's Fordo uranium enrichment facility.

The site is buried deep underground — and to eliminate it, Israel may need the 30,000-pound (14,000-kilogram) GBU-57 Massive Ordnance Penetrator, a U.S. bunker-busting bomb that uses its weight and sheer kinetic force to reach deeply buried targets. Israel does not have the munition or the bomber needed to deliver it. The penetrator is currently delivered by the B-2 stealth bomber.

Iran's foreign minister, Abbas Araghchi, appeared to make a veiled plea Monday for the U.S. to step in and negotiate an end to hostilities between Israel and Iran.

In a post on X, Araghchi wrote that if Trump is genuine about diplomacy and interested in stopping this war, next steps are consequential.

It takes one phone call from Washington to muzzle someone like Netanyahu, Iran's top diplomat wrote. That may pave the way for a return to diplomacy.

The message to Washington was sent as the latest talks between the U.S. and Iran were canceled over the weekend after Israel's surprise bombardment.

On Sunday, Araghchi said that Iran will stop its strikes if Israel does the same.

Trump ended the post with, Everyone should immediately evacuate Tehran! White House press secretary Karoline Leavitt said on social media shortly after Trump's post that he was departing the summit on Monday night, leaving for Washington a day early due to the intensifying conflict between Israel and Iran.

Tehran is home to around 9.5 million people. Earlier Monday, Israel's military issued an evacuation warning affecting up to 330,000 people in a part of central Tehran that includes the country's state TV and police headquarters, as well as three large hospitals, including one owned by Iran's paramilitary Revolutionary Guard. Israel's military has issued similar evacuation warnings for civilians in parts of Gaza and Lebanon ahead of strikes.

State-run television abruptly stopped a live broadcast after the station was hit, according to Iran's state-run news agency.

While on the air, an Iranian state television reporter said the studio was filling with dust after the sound of aggression against the homeland. Suddenly, an explosion occurred, cutting the screen behind her as she hurried off camera.

The broadcast quickly switched to prerecorded programs. The station later said its building was hit by four bombs.

An anchor said on air that a few colleagues had been hurt, but their families should not be worried. The network said its live programs were transferred to another studio.

Israeli military spokesperson Brig. Gen. Effie Defrin said his country's forces had achieved full aerial superiority over Tehran's skies.

The military said it destroyed more than 120 surface-to-surface missile launchers in central Iran, a third of Iran's total, as well as two F-14 planes that Iran used to target Israeli aircraft and multiple launchers just before they launched ballistic missiles towards Israel.

Israeli military officials also said fighter jets had struck 10 command centers in Tehran belonging to Iran's Quds Force, an elite arm of its Revolutionary Guard that conducts military and intelligence operations outside Iran.

The Israeli strikes amount to a deep and comprehensive blow to the Iranian threat, Defrin said.

Elsewhere, three drones struck South Pars, Iran's main gas production center, according to Iranian state news. The report did not specify the extent of the damage.

Iran, meanwhile, announced it had launched some 100 missiles and vowed further retaliation for the sweeping attacks on its military and nuclear infrastructure that have killed at least 224 people in the country since Friday.

So far, 24 people have been killed in Israel and more than 500 injured, Israeli officials said, after Iran launched more than 370 missiles and hundreds of drones.

One missile fell near the American consulate in Tel Aviv, with its blast waves causing minor damage, U.S. Ambassador Mike Huckabee said on X. He added that no American personnel were injured.

The latest conflict began when Israel launched an assault on Iran's top military leaders, uranium enrichment sites and nuclear scientists that it said was necessary to prevent its longtime adversary from getting any closer to building an atomic weapon.

Iran maintains that its nuclear program is peaceful, and the U.S. and others have assessed that Tehran has not pursued a nuclear weapon since 2003. But the head of the International Atomic Energy Agency has repeatedly warned that the country has enough enriched uranium to make several nuclear bombs if it chooses to do so.

Iran has retaliated by firing waves of ballistic missiles at Israel. The back-and-forth has raised concerns about all-out war between the countries and propelled the region, already on edge, into even greater upheaval.

Powerful explosions rocked Tel Aviv shortly before dawn Monday, sending plumes of black smoke into the sky over the coastal city.

Authorities in the central Israeli city of Petah Tikva said Iranian missiles hit a residential building there, charring concrete walls, shattering windows and ripping the walls off multiple apartments.

Iranian missiles also hit an oil refinery in the northern city of Haifa for the second night in a row. The early morning strike killed three workers, ignited a significant fire and damaged a building, Israel's fire and rescue services said. The workers were sheltering in the building's safe room when the impact caused a stairwell to collapse, trapping them inside.

Firefighters rushed to extinguish the fire and rescue them, but the three died before rescuers could reach them.

The Israeli Magen David Adom emergency service also reported that five people were killed in the strikes in central Israel.

Petah Tikva resident Yoram Suki rushed with his family to a shelter after hearing an air-raid alert. They emerged after it was over to find his apartment destroyed.

Despite losing his home, he urged Netanyahu to keep up the attacks on Iran.

It's totally worth it, the 60-year-old said. This is for the sake of our children and grandchildren.

In addition to those killed, the emergency service said paramedics evacuated another 87 wounded people to hospitals, while rescuers were still searching for residents trapped beneath the rubble of their homes.

When we arrived at the scene of the rocket strike, we saw massive destruction, said Dr. Gal Rosen, a paramedic with the service who said he rescued a 4-day-old baby as fires blazed from the building.