How poo could be a silver bullet in tracking COVID-19

Published April 29, 2020, 12:00 AM

by manilabulletin_admin

By Agence France-Presse

Since the beginning of the epidemic, researchers across the world have been tracing the spread of the coronavirus through wastewater and sewage.

From the first outbreak in China, several scientific studies have picked up the clear presence of COVID-19 in patients’ stools.

Testing human sewage could now become a key way of tracking the pandemic’s spread — and a precious early warning system for a feared second wave.

Researchers have found genetic traces of Sars-Cov-2 — as the virus is officially known — in wastewater in toilets, sewers and sewage farms from Brisbane to Paris and Amsterdam.

These discoveries pose “no risk” to public health, insisted Luca Lucentini, water quality director at the Italian Institute Superior of Health (ISS), after several tests came up positive in Rome and Milan.

Experts say drinking water in countries with strict treatment procedures is also safe.

While the presence of the virus in feces does not mean that it can be transmitted through them, being exposed to effluent “could pose a health risk,” warned researchers Willemijn Lodder and Ana Maria de Roda Husman from the Dutch Centre for Infectious Diseases Control in a paper in The Lancet.

The center reported late last month that it detected genetic material from the virus in wastewater in Amsterdam.

‘Precisely followed deaths’ 

But the pair also insist that wastewater could a precious “data source, indicating if the virus is circulating in the human population”.

It could even allow experts to “track the virus”, French virologist Professor Vincent Marechal of the Sorbonne university in Paris told AFP.

In a study of wastewater in Paris — which has yet to be validated by other scientists — Marechal and his team found that the rise in levels of genetic material from the virus in water “followed precisely the number of (coronavirus) deaths”.

Marechal is now call for a national wastewater warning system in France which might help “anticipate a second wave” of the virus.

Given the large number of coronavirus cases that have little or no symptoms, wastewater testing could signal the presence of the virus even before the first cases are clinically confirmed in areas untouched by the epidemic or where it has ebbed.

“That would allow barrier measures to be put place and give us time, a key element with this epidemic,” Marechal added.

Such a system has already worked against other viruses.

In a study published in 2018, researchers showed how polio being detected in wastewater in Israel in 2013 gave time for a vaccination campaign to be launched, which meant no child was paralyzed by the disease.

Call for global test network 

For the Sars-Cov-2, wastewater studies in several countries are still at an early stage. But some scientists are enthusiastic about their potential.

“It could be used as an early warning tool for pandemic surveillance,” Dr. Warish Ahmed, of the Australian public research agency CSIRO, told AFP.

Having found the virus in wastewater in Queensland, he said it could also be a key indicator to show if lockdown and other measures were working.

“Access to this type of data could underpin… a surveillance program to identify areas where there is evidence of COVID-19 outbreaks, without requiring testing of all individuals,” Dr Warish added.

He said although it was a “cost effective way of tracking community-level infection”, he warned that it should be used “in combination with other measures, such as the testing of individuals.”

Its relative cheapness would also make it useful for countries that “don’t have the technical or logistic means to test the carriers” of the virus, Marechal said.

He has called on the World Health Organization to set up a worldwide wastewater virus detection network, which would help combat other killer diseases beyond COVID-19.

“It could be essential in Africa,” he said. “To protect a population, you have to safeguard water quality.”